Posts categorized “Venlafaxine Withdrawal”.

Venlafaxine Withdrawal

Venlafaxine hydrochloride is useful for treating depression in the grownups. It is a prescription medication sold by Effexor, a brand name. It is among the most widely preferred antidepressant medicine on the planet. According to the clinical analysis, the operation mode of the drug is simple but effective wherein it balances the brain chemicals that are unbalanced in depression. This drug belongs to the category of the Selective Serotonin and Norepinephrine Re-uptake Inhibitors (SSNRIs). This is because the drug hinders the two chemicals namely, serotonin and norepinephrine, present in the brain as well as averts their reabsorption. Due to its this capacity, it is useful in combating major depressive disorder, panic disorder, social anxiety disorder, and generalized anxiety disorder.

Just the case with any other antidepressant, Venlafaxine has its own withdrawal symptoms. Venlafaxine withdrawal is actually among the major side effects of the drug, which occurs when the patients of depression stop taking it immediately. When the symptoms of depression vanish, the patients suddenly stop taking the medicines. However, they do not realize that their sudden halt can also adversely affect their brain where this drug show a positive impact. This is because the brain is now completely dependent on the drug to function properly and halting the drug completely all of a sudden can trigger adverse reactions. This is the reason why experts appeal to the patients to consult the doctor or physician before stopping Venlafaxine. Usually, the intake of the drug is lessened not suddenly, but in a period of over two weeks. This is essential to get rid of the Venlafaxine side effects or sudden discontinuation effects, read through the following symptoms.

Signs of Flu

One of the common Venlafaxine withdrawal symptoms is the set of flu symptoms such as cough, headache, fever, muscle ache, and body pain. Once you stop using the drug abruptly, these signs tend might take place in some days and can remain for up to more than a month’s time. The reliving news here is that these signs are mild, which are alleviated with time if you lessen the drug usage in the correct manner.

Adverse Effects on the Brain

Stopping the use of Venlafaxine abruptly increases the chances of many bad reactions in the brain. Due to this, you might experience fatigue, dizziness, impaired coordination, tremors, headache, strange sensory feelings, sleeping difficulty, drowsiness, and nightmares. Even worse is the fact that these signs can be moderate to severe, which can later affect your ability to deal with the daily activities. In case you experience these symptoms, it is advisable for you to be vigilant while performing the usual daily tasks such as cooking, driving, and other concentration related activities.

Unfavorable Effects on the Gastrointestinal Tract

You might experience symptoms such as vomiting, nausea, diarrhea, dry mouth, and loss of appetite after Venlafaxine withdrawal.

Unpleasant Behavioral Changes

A sudden change that is not normal affects your behavior with others. There are many adverse effects on your usual behavior that tend to spoil your relationships. Portraying anxiety, agitation, nervousness, bad mood, confusion, and irritation are all the possible symptoms of Venlafaxine withdrawal. In case you used to take a big dose for a long time, these symptoms show off with an increased frequency. In this case, the patient is again put on the previous dose that is reduced gradually henceforth.

Depression and Suicide

This symptom reverses the very aim of the drug. In patients with worsening depression featuring suicidal trials, even lowering the dose is done with great care. Therefore, you can imagine what can happen if you stop taking the dose all of a sudden. In such cases, the patients need very close supervision.

Other Signs

– Burning or tingling sensation
– Insomnia
– Feeling of ants crawling on your skin
– Frequently changing emotions

Although a majority of these Venlafaxine withdrawal symptoms reduce with the passage of time and without any treatment, it is still advisable to visit your doctor in case you witness these effects. Nevertheless, the best way to prevent them is to lower the dose slowly by consulting the doctor.

Venlafaxine Dosage

Venlafaxine dosage is usually 75-225 mg daily once a patient is titrated up to optimal benefit, but it is started slowly to avoid vanlafaxine side effects.

Venlafaxine is a medication that stops reuptake of serotonin and norepinephrine and so is known as a serotonin and norepinephrine reuptake inhibiror(SNRI). By increasing the amount of serotonin and norepinphrine in the fluid between the brain nerve cells if acet to rebalanceg the neurotransmitters to help with depression, social phobia and generalized anxiety disorder. Venlafaxine is also used to help people with anxiety to cope with daily life.

Venlafaxine dosage is usually started with one week of 37.5 mg daily prior to increasing to the lowest typical effective venlafaxine dosage of 75mg daily, but it is halved in people with liver and kidney problems. Like other SSRI and SNRI medications it usually takes several weeks to achieve the desired benefits, so patience is needed when using these drugs. Venlafaxine has a very short drug half-life, so it does not remain in the body for long a time, and most patients use a controlled released capsule to absorb the venlafaxine dosage slowly into the system. The maximum venlafaxine dosage is 225 mg daily, and the effect on norepinephrine reuptake is most noted at the higher doses, primarily doses above 150 mg daily.

Sexual dysfunction, primarily ejaculatory delay in males and orgasm difficulty in women is a very common side effect of venlafaxine. This can be a significant enough problem for some patients that they do not stay on treatment. Venlafaxine is not recommended in pregnancy due to lack of studies showing safety. Venlafaxine also showed increase in suicidal ideation during first few weeks of treatment, and this needs to be watched for by patients and family. Venlafaxine is best not abruptly stopped; it should be tapered before stopping the medication in full to avoid venlafaxine withdrawal syndrome. The short half-life of venlafaxine makes this syndrome more common than with SSRI medications with longer serum half-lives. People with liver and kidney failure should have their dose reduced in most cases, and your physician can help you assess this issue.



Venlafaxine is a drug that is categorized as one of the most widely used antidepressant therapies inthe world. Medical analysis have shown that the mode at which the drug operates is based on avery simple yet very effective process.  This involves the balancing of brain chemicals which medical analysis have shown that onthe event of depression they are unbalanced to a hugedegree. Venlafaxine can be categorized also in the SSNRIs type of drugs otherwise known by practitioners in health as the selective serotonin and norepinephrine re-uptake inhibitors. The conventional use of the drug as we have quite rightly noted is restricted to the treatment of depression all be it can also be effective in doing away with issues of anxiety and panic.

The wide application of the drug and the continuing recognition that is indeed effective has pushed many people to it others even beyond the limits. The reality about Venlafaxine even ifit is a very effective antidepressant remedy is that, it is a very strong drug and should be taken with moderation and caution. One thing that you should be advised when you begin treatment using the drug is that, you have no choice but to seek the prescription of a qualified health practitioner or expert. Furthermore, you are also advised to always ensure that you are notallergic to the drug as this can also have very regrettable consequences. Here is the best resource online about Venlafaxine side effects. The treatment of depression with the drug normally takes a period of 12 weeks and during this period; the effectiveness of the drug will also be determined by external factors that many of us should be aware of. To start with the issue of taking prescription from a qualified doctor orpharmacist is just inevitable and cannot be emphasized further than this.

The patient should be observed very keenly to ensure that all changes in mood are reported and during the entire period of medication the consultancy and touch of the doctor is highly recommended. Patients with previous history of disease such as epilepsy, high blood pressure or even high cholesterol may not be fit for the basic dose of the drug and the best thing here is to seek alternatives from an expert in the field of health.  Although there are special conditions where Venlafaxine can be used for pregnant mothers, itis also very important to underscore the fact that sometimes this may prove to be very tricky and this is because there is a very huge chance that the drug can have very severe health repercussions on the unborn child and further on after birth since the drug can contaminate breast milk. Venlafaxine withdrawal is one of the more serious side effects of Venlafaxine.

Pregnant mothers or those wishing to get babies during the period of the medication should consult their doctors to be advised accordingly and in most cases this will include either postponing the pregnancy incase of those planning to get babies or postponing the treatment for those who are pregnant.  However, early stages of pregnancy may reduce the
risk to some degree although not considerably as such.